Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NF0Q
|
|||
| Former ID |
DIB012456
|
|||
| Drug Name |
ZD-0947
|
|||
| Synonyms |
AZD-0947
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Overactive bladder [ICD-11: GC50.0; ICD-10: N32.8] | Discontinued in Phase 2 | [1] | |
| Company |
AstraZeneca plc
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H13F3N2O
|
|||
| Canonical SMILES |
C1CC2=C(C(C=C(N2)C(F)(F)F)C3=CC=CC(=C3)C#N)C(=O)C1
|
|||
| InChI |
1S/C17H13F3N2O/c18-17(19,20)15-8-12(11-4-1-3-10(7-11)9-21)16-13(22-15)5-2-6-14(16)23/h1,3-4,7-8,12,22H,2,5-6H2/t12-/m0/s1
|
|||
| InChIKey |
RUVMMEREJMHLOS-LBPRGKRZSA-N
|
|||
| CAS Number |
CAS 172649-40-0
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009535) | |||
| REF 2 | Effects of ZD6169 and ZD0947, 2 potassium adenosine triphosphate channel openers, on bladder function of spinalized rats. J Urol. 2002 Aug;168(2):837-42. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.