Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NH6F
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| Former ID |
DIB013611
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| Drug Name |
VUF-8929
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| Synonyms |
140890-71-7; Vuf 8929; AC1O5RNQ; N-(2-Bis(4-fluorophenyl)methoxy)ethyl-(2-phenyl)ethylamine maleate; Benzeneethanamine, N-(2-(bis(4-fluorophenyl)methoxy)ethyl)-, (2Z)-2-butenedioate (1:1)
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| Drug Type |
Small molecular drug
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| Indication | Heart failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9; ICD-9: 428] | Terminated | [1] | |
| Company |
Organon BioSciences
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| Structure |
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Download2D MOL |
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| Formula |
C27H27F2NO5
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| Canonical SMILES |
CCN(CCC1=CC=CC=C1)OCC2=C(C=C(C=C2)F)C3=CC=C(C=C3)F.C(=CC(=O)O)C(=O)O
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| InChI |
1S/C23H23F2NO.C4H4O4/c1-2-26(15-14-18-6-4-3-5-7-18)27-17-20-10-13-22(25)16-23(20)19-8-11-21(24)12-9-19;5-3(6)1-2-4(7)8/h3-13,16H,2,14-15,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
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| InChIKey |
GMPALWBPFJCWPO-BTJKTKAUSA-N
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| CAS Number |
CAS 140890-71-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009533) | |||
| REF 2 | In vitro and in vivo characterization of a calcium modulator of the diphenylalkylamine type with selective coronary dilatory properties. Arzneimittelforschung. 1997 Nov;47(11):1211-8. | |||
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