Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O0AR
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| Drug Name |
RP-71483
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| Synonyms |
138279-55-7
Click to Show/Hide
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H28N6O4
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| Canonical SMILES |
C1CC2=CC=CC=C2N(C1)C(=O)CN(C3=CC=CC4=C3N=CC=C4)C(=O)CNC(=O)NC5=CC=CC(=C5)C=NO
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| InChI |
1S/C30H28N6O4/c37-27(19-32-30(39)34-24-12-3-7-21(17-24)18-33-40)36(26-14-4-9-23-10-5-15-31-29(23)26)20-28(38)35-16-6-11-22-8-1-2-13-25(22)35/h1-5,7-10,12-15,17-18,40H,6,11,16,19-20H2,(H2,32,34,39)/b33-18-
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| InChIKey |
MKQFGVTYYCUUEG-OHUYPAJKSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastrin/cholecystokinin type B receptor (CCKBR) | Target Info | Modulator | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gastric acid secretion | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Secretion of Hydrochloric Acid in Parietal Cells | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacological properties of ureido-acetamides, new potent and selective non-peptide CCKB/gastrin receptor antagonists. Eur J Pharmacol. 1994 Sep 12;262(3):233-45. | |||
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