Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O4MK
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| Former ID |
DNC012312
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| Drug Name |
3-Chloro-9H-beta-carboline
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| Synonyms |
3-chloro-9H-pyrido[3,4-b]indole; CHEMBL298561; 91985-80-7; 3-Chloro-9H-beta-carboline; 3-chloro-b-carboline; 3-Chloro-beta-carboline; AC1O2G3D; CHEMBL496742; SCHEMBL10642293; BDBM50013805; 9H-Pyrido[3,4-b]indole, 3-chloro-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H7ClN2
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=CC(=NC=C3N2)Cl
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| InChI |
1S/C11H7ClN2/c12-11-5-8-7-3-1-2-4-9(7)14-10(8)6-13-11/h1-6,14H
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| InChIKey |
JDYLMOJCIKYTGV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
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