Drug Information
Drug General Information | Top | |||
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Drug ID |
D0O5ZG
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Former ID |
DNC004018
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Drug Name |
1-Methoxy-6-phenyl-6H-benzo[c]chromene
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Synonyms |
CHEMBL63422; 1-Methoxy-6-phenyl-6H-benzo[c]chromene
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C20H16O2
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Canonical SMILES |
COC1=CC=CC2=C1C3=CC=CC=C3C(O2)C4=CC=CC=C4
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InChI |
1S/C20H16O2/c1-21-17-12-7-13-18-19(17)15-10-5-6-11-16(15)20(22-18)14-8-3-2-4-9-14/h2-13,20H,1H3
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InChIKey |
SZYXTCHBPGBQPM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Glucocorticoid receptor messenger RNA (GCR mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
NetPath Pathway | IL2 Signaling Pathway | |||
TCR Signaling Pathway | ||||
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | |||
Signaling events mediated by HDAC Class II | ||||
FOXA2 and FOXA3 transcription factor networks | ||||
Glucocorticoid receptor regulatory network | ||||
Regulation of Androgen receptor activity | ||||
AP-1 transcription factor network | ||||
Reactome | BMAL1:CLOCK,NPAS2 activates circadian gene expression | |||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
SIDS Susceptibility Pathways | ||||
Endoderm Differentiation | ||||
Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | ||||
Adipogenesis | ||||
Circadian Clock | ||||
Nuclear Receptors |
References | Top | |||
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REF 1 | Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists. Bioorg Med Chem Lett. 2004 May 3;14(9):2079-82. |
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