Drug Information
Drug General Information | Top | |||
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Drug ID |
D0O7MW
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Former ID |
DNC011274
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Drug Name |
(5-methoxy-1H-indol-3-yl)methanamine
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Synonyms |
(5-methoxy-1H-indol-3-yl)methanamine; 60523-82-2; 5-Methoxy-1h-indol-3-methylamine; 3-(AMINOMETHYL)-5-METHOXYINDOLE; CHEMBL1276050; 5-METHOXYINDOLE-3-METHYLAMINE; SCHEMBL3976318; CTK5B1636; DTXSID20563182; MolPort-006-831-850; ZX-AN081076; ALBB-030269; FCH853008; BDBM50330861; 9026AB; ZINC20269183; AKOS005214650; MB03907; CM-1862; SC-45599; KB-43524; AJ-76727; AK112525; ST2402466; DB-012273; AX8104451; FT-0691098; 4CH-017193; 1-(5-METHOXY-1H-INDOL-3-YL)METHANAMINE
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H12N2O
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Canonical SMILES |
COC1=CC2=C(C=C1)NC=C2CN
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InChI |
1S/C10H12N2O/c1-13-8-2-3-10-9(4-8)7(5-11)6-12-10/h2-4,6,12H,5,11H2,1H3
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InChIKey |
CAHOMULUOHSWPI-UHFFFAOYSA-N
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CAS Number |
CAS 60523-82-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2B receptor (HTR2B) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify no... J Med Chem. 2010 Nov 11;53(21):7573-86. |
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