Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O9VW
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| Former ID |
DIB000581
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| Drug Name |
Lanperisone
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| Synonyms |
NK-433
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| Drug Type |
Small molecular drug
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| Indication | Musculoskeletal disorder [ICD-11: FA00-FC0Z; ICD-10: R25-R29] | Phase 3 | [1] | |
| Company |
Nippon Kayaku Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C15H18F3NO
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| Canonical SMILES |
CC(CN1CCCC1)C(=O)C2=CC=C(C=C2)C(F)(F)F
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| InChI |
1S/C15H18F3NO/c1-11(10-19-8-2-3-9-19)14(20)12-4-6-13(7-5-12)15(16,17)18/h4-7,11H,2-3,8-10H2,1H3/t11-/m1/s1
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| InChIKey |
RYZCWZZJFAKYHX-LLVKDONJSA-N
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| CAS Number |
CAS 116287-14-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.4 (SCN4A) | Target Info | Modulator | [1] |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels. J Pharmacol Exp Ther. 2005 Dec;315(3):1237-46. | |||
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