Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OK9X
|
|||
| Former ID |
DCL000477
|
|||
| Drug Name |
AZD6765
|
|||
| Synonyms |
Lanicemine; 153322-05-5; AZD6765; UNII-9TMU325RK3; AR-R15896AR; ARL 15896; 9TMU325RK3; AZD-6765; (1S)-1-phenyl-2-(pyridin-2-yl)ethan-1-amine; Lanicemine [INN]; FPL 15896; AR-R 15896; GTPL7681; CHEMBL467084; SCHEMBL1422817; ZINC6163; AR-R-15896AR; MolPort-030-004-688; AKOS026744074; DB11889; AJ-08269; (1S)-1-phenyl-2-pyridin-2-ylethanamine; (+)-2-((S)-beta-Aminophenethyl)pyridine; ( )-2-(S)-beta-Aminophenethyl-pyridine.; Z2286637868
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2] | Discontinued in Phase 2 | [1], [2] | |
| Company |
AstraZeneca
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C13H14N2
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)C(CC2=CC=CC=N2)N
|
|||
| InChI |
1S/C13H14N2/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12/h1-9,13H,10,14H2/t13-/m0/s1
|
|||
| InChIKey |
FWUQWDCOOWEXRY-ZDUSSCGKSA-N
|
|||
| CAS Number |
CAS 153322-05-5
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Antagonist | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7681). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026805) | |||
| REF 3 | Clinical pipeline report, company report or official report of AstraZeneca (2009). | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.