Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OR2V
|
|||
| Drug Name |
N-(arylamino)sulfonamide derivative 1
|
|||
| Synonyms |
PMID28594589-Compound-TABLE3c8
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
Ardea Biosciences
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H17F4IN2O4S
|
|||
| Canonical SMILES |
C1CC1(CC(CO)O)S(=O)(=O)NC2=C(C(=C(C=C2F)F)F)NC3=C(C=C(C=C3)I)F
|
|||
| InChI |
1S/C18H17F4IN2O4S/c19-11-5-9(23)1-2-14(11)24-17-15(22)12(20)6-13(21)16(17)25-30(28,29)18(3-4-18)7-10(27)8-26/h1-2,5-6,10,24-27H,3-4,7-8H2
|
|||
| InChIKey |
DDZSGPZIFZFUSF-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ERK activator kinase (MEK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | ERK activator kinase (MEK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | MEK inhibitors in oncology: a patent review (2015-Present).Expert Opin Ther Pat. 2017 Aug;27(8):887-906. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.