Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OT8R
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| Drug Name |
Pyridine-carboximide derivative 1
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| Synonyms |
PMID25470667-Compound-Figure5-5
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| Drug Type |
Small molecular drug
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| Company |
SCHERING CORPORATION TING, Pauline, C. LEE, Joe, F. ASLANIAN, Robert, G
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| Structure |
 |
Download2D MOL |
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| Formula |
C31H27N3O5
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| Canonical SMILES |
CC1=C(OC2=C1C=C(C=C2)C3=CC=CC=C3)C(=O)NC4=CN=C(C=C4)C5=CN=C(C=C5)OCC(C)(C)C(=O)O
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| InChI |
1S/C31H27N3O5/c1-19-24-15-21(20-7-5-4-6-8-20)9-13-26(24)39-28(19)29(35)34-23-11-12-25(32-17-23)22-10-14-27(33-16-22)38-18-31(2,3)30(36)37/h4-17H,18H2,1-3H3,(H,34,35)(H,36,37)
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| InChIKey |
WBSJFAVPZLMOLD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Diacylglycerol acyltransferase 1 (DGAT1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Diacylglycerol acyltransferase 1 (DGAT1) | Target's Patent Info | [1] | |
| BioCyc | Triacylglycerol biosynthesis | |||
| KEGG Pathway | Glycerolipid metabolism | |||
| Retinol metabolism | ||||
| Metabolic pathways | ||||
| Fat digestion and absorption | ||||
| Pathwhiz Pathway | Retinol Metabolism | |||
| Reactome | Acyl chain remodeling of DAG and TAG | |||
| Triglyceride Biosynthesis | ||||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Statin Pathway | ||||
| Triacylglyceride Synthesis | ||||
| Glycerophospholipid biosynthesis | ||||
| Fatty acid, triacylglycerol, and ketone body metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58. | |||
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