Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OW6Q
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| Former ID |
DNC006902
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| Drug Name |
2,3'-diamino-3,4,4',5-tetramethoxy-(Z)-stillbene
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| Synonyms |
SCHEMBL4220471
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C18H22N2O4
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| Canonical SMILES |
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2N)OC)OC)OC)N
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| InChI |
1S/C18H22N2O4/c1-21-14-8-6-11(9-13(14)19)5-7-12-10-15(22-2)17(23-3)18(24-4)16(12)20/h5-10H,19-20H2,1-4H3/b7-5-
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| InChIKey |
ONFPNROXTUMLBU-ALCCZGGFSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tubulin beta (TUBB) | Target Info | Inhibitor | [1] |
| Tubulin beta-2 chain (TUBB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Phagosome | |||
| Gap junction | ||||
| Pathogenic Escherichia coli infection | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| EGFR1 Signaling Pathway | ||||
| Panther Pathway | Cytoskeletal regulation by Rho GTPase | |||
| Huntington disease | ||||
| Reactome | Regulation of PLK1 Activity at G2/M Transition | |||
| Loss of Nlp from mitotic centrosomes | ||||
| Recruitment of mitotic centrosome proteins and complexes | ||||
| Loss of proteins required for interphase microtubule organization?from the centrosome | ||||
| Anchoring of the basal body to the plasma membrane | ||||
| WikiPathways | Parkin-Ubiquitin Proteasomal System pathway | |||
| Pathogenic Escherichia coli infection | ||||
| Mitotic G2-G2/M phases | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents. J Med Chem. 2006 Oct 19;49(21):6412-5. | |||
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