Drug Information
Drug General Information | Top | |||
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Drug ID |
D0P1CV
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Former ID |
DIB004263
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Drug Name |
PHA-793887
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Synonyms |
Cyclin-dependent kinase inhibitor (cancer), Nerviano
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Drug Type |
Small molecular drug
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Phase 1 | [1] | |
Company |
Nerviano Medical Sciences Srl
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Structure |
Download2D MOL |
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Formula |
C19H31N5O2
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Canonical SMILES |
CC(C)CC(=O)NC1=NNC2=C1CN(C2(C)C)C(=O)C3CCN(CC3)C
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InChI |
1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)
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InChIKey |
HUXYBQXJVXOMKX-UHFFFAOYSA-N
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CAS Number |
CAS 718630-59-2
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:91371
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References | Top | |||
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REF 1 | A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected h... Cell Cycle. 2011 Mar 15;10(6):963-70. | |||
REF 2 | Liposarcoma: molecular genetics and therapeutics. Sarcoma. 2011;2011:483154. |
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