Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P8SU
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| Former ID |
DNC008257
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| Drug Name |
(R)-1-(4-nitrophenethyl)-2-methylpyrrolidine
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| Synonyms |
CHEMBL440996; SCHEMBL1574678; PFZYNGPCNCRLFU-LLVKDONJSA-N; BDBM50372333; ZINC29131354
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H18N2O2
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| Canonical SMILES |
CC1CCCN1CCC2=CC=C(C=C2)[N+](=O)[O-]
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| InChI |
1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m1/s1
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| InChIKey |
PFZYNGPCNCRLFU-LLVKDONJSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. | |||
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