Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Q0GY
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Former ID |
DIB013666
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Drug Name |
IW-1221
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Synonyms |
CRTH2 inhibitor (asthma), Ironwood
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Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Investigative | [1] | |
Company |
Ironwood Pharmaceuticals Inc
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Target and Pathway | Top | |||
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Target(s) | Prostaglandin D2 receptor 2 (PTGDR2) | Target Info | Inhibitor | [1] |
Reactome | Prostanoid ligand receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339). |
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