Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q0IE
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| Former ID |
DNC012556
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| Drug Name |
PT-110
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| Synonyms |
181305-20-4; Thiourea, N-(5-chloro-2-pyridinyl)-N'-(2-(3-cyano-2,6-difluorophenyl)ethyl)-; N-(2-(3-Cyano-2,6-difluorophenethyl))-N'-(2-(5-chloropyridyl))thiourea; 1-(5-chloropyridin-2-yl)-3-[2-(3-cyano-2,6-difluorophenyl)ethyl]thiourea; N-[2-(3-Cyano-2,6-difluorophenethyl)]-N'-[2-(5-chloropyridyl)]thiourea; Thiourea, N-(5-chloro-2-pyridinyl)-N'-[2-(3-cyano-2,6-difluorophenyl)ethyl]-; PT-110; AC1MHDLU; LY300046HCl Analog 4; CHEMBL319224; BDBM2120; DTXSID20171100
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11ClF2N4S
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| Canonical SMILES |
C1=CC(=NC=C1Cl)NC(=S)NCCC2=C(C=CC(=C2F)C#N)F
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| InChI |
1S/C15H11ClF2N4S/c16-10-2-4-13(21-8-10)22-15(23)20-6-5-11-12(17)3-1-9(7-19)14(11)18/h1-4,8H,5-6H2,(H2,20,21,22,23)
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| InChIKey |
OZXHOQRXBCCXFI-UHFFFAOYSA-N
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| CAS Number |
CAS 181305-20-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity r... J Med Chem. 1996 Oct 11;39(21):4261-74. | |||
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