Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q0YN
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| Former ID |
DIB001351
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| Drug Name |
SORAPRAZAN
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| Synonyms |
BY-359; Soraprazan; 2,3-Dimethyl-7(R)-(2-methoxyethoxy)-9(R)-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridin-8(R)-ol
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| Drug Type |
Small molecular drug
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| Indication | Peptic ulcer [ICD-11: DA61] | Discontinued in Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H25N3O3
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| Canonical SMILES |
CC1=C(N2C=CC3=C(C2=N1)NC(C(C3OCCOC)O)C4=CC=CC=C4)C
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| InChI |
1S/C21H25N3O3/c1-13-14(2)24-10-9-16-18(21(24)22-13)23-17(15-7-5-4-6-8-15)19(25)20(16)27-12-11-26-3/h4-10,17,19-20,23,25H,11-12H2,1-3H3/t17-,19-,20-/m1/s1
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| InChIKey |
PWILYDZRJORZDR-MISYRCLQSA-N
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| CAS Number |
CAS 261944-46-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015211) | |||
| REF 2 | Soraprazan: setting new standards in inhibition of gastric acid secretion.J Pharmacol Exp Ther.2007 Jun;321(3):866-74. | |||
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