Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q1HF
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| Former ID |
DIB018793
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| Drug Name |
NCGC00167772-01
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| Synonyms |
10-DEBC
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C20H25ClN2O
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| Canonical SMILES |
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl
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| InChI |
1S/C20H25ClN2O/c1-3-22(4-2)13-7-8-14-23-17-9-5-6-10-19(17)24-20-12-11-16(21)15-18(20)23/h5-6,9-12,15H,3-4,7-8,13-14H2,1-2H3
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| InChIKey |
GYBXAGDWMCJZJK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:94104
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serine/threonine-protein kinase pim-1 (PIM1) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Jak-STAT signaling pathway | |||
| MicroRNAs in cancer | ||||
| Acute myeloid leukemia | ||||
| NetPath Pathway | IL9 Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | ||||
| Pathway Interaction Database | GMCSF-mediated signaling events | |||
| Validated targets of C-MYC transcriptional activation | ||||
| Role of Calcineurin-dependent NFAT signaling in lymphocytes | ||||
| IL5-mediated signaling events | ||||
| IL3-mediated signaling events | ||||
| C-MYB transcription factor network | ||||
| WikiPathways | Ectoderm Differentiation | |||
| Hematopoietic Stem Cell Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2158). | |||
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