Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q1HK
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| Former ID |
DNC011816
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| Drug Name |
2-Dipropylamino-1,2,3,4-tetrahydro-anthracen-9-ol
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| Synonyms |
CHEMBL62297; 2-Dipropylamino-1,2,3,4-tetrahydro-anthracen-9-ol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H27NO
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| Canonical SMILES |
CCCN(CCC)C1CCC2=CC3=CC=CC=C3C(=C2C1)O
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| InChI |
1S/C20H27NO/c1-3-11-21(12-4-2)17-10-9-16-13-15-7-5-6-8-18(15)20(22)19(16)14-17/h5-8,13,17,22H,3-4,9-12,14H2,1-2H3
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| InChIKey |
TXKDLYBWCJNMHU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile, Bioorg. Med. Chem. Lett. 3(10):2035-2038 (1993). | |||
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