Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q3SP
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| Former ID |
DIB009504
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| Drug Name |
NPS-1392
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
NPS Pharmaceuticals Inc
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H17F2N
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| Canonical SMILES |
CC(CN)C(C1=CC(=CC=C1)F)C2=CC(=CC=C2)F
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| InChI |
1S/C16H17F2N/c1-11(10-19)16(12-4-2-6-14(17)8-12)13-5-3-7-15(18)9-13/h2-9,11,16H,10,19H2,1H3/t11-/m0/s1
|
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| InChIKey |
WEEQOTXCUZRCLD-NSHDSACASA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013127) | |||
| REF 2 | Synthesis, biological activity, and absolute stereochemical assignment of NPS 1392: a potent and stereoselective NMDA receptor antagonist. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1915-20. | |||
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