Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q3UL
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| Former ID |
DPR000090
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| Drug Name |
PD-160170
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| Synonyms |
NCGC00092332-01; BRD-K12079898-001-01-8; 5-nitro-6-(2-propan-2-ylphenyl)sulfonyl-quinolin-8-amine
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| Drug Type |
Small molecular drug
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| Indication | Heart disease [ICD-11: BA41-BA42] | Preclinical | [1] | |
| Hypertension [ICD-11: BA00-BA04] | Preclinical | [1] | ||
| Obesity [ICD-11: 5B81; ICD-10: E66] | Preclinical | [1] | ||
| Company |
Parke CDavis
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H17N3O4S
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| Canonical SMILES |
CC(C)C1=CC=CC=C1S(=O)(=O)C2=C(C3=C(C(=C2)N)N=CC=C3)[N+](=O)[O-]
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| InChI |
1S/C18H17N3O4S/c1-11(2)12-6-3-4-8-15(12)26(24,25)16-10-14(19)17-13(7-5-9-20-17)18(16)21(22)23/h3-11H,19H2,1-2H3
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| InChIKey |
YUVNGBZROXQYQH-UHFFFAOYSA-N
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| CAS Number |
CAS 181468-88-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:92206
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuropeptide Y receptor type 1 (NPY1R) | Target Info | Antagonist | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| Endothelin Pathways | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60. | |||
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