Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q4IM
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| Former ID |
DNC005298
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| Drug Name |
JWH-237
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| Synonyms |
JWH-237; UNII-NR611I7X19; CHEMBL188822; NR611I7X19; 2-(3-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone; 864445-56-7; JWH 203 3-chlorophenyl isomer; KURUPMPUIIQATM-UHFFFAOYSA-N; ZINC28463001; BDBM50170332; 2-(3-Chloro-phenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone; Ethanone, 2-(3-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H22ClNO
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| Canonical SMILES |
CCCCCN1C=C(C2=CC=CC=C21)C(=O)CC3=CC(=CC=C3)Cl
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| InChI |
1S/C21H22ClNO/c1-2-3-6-12-23-15-19(18-10-4-5-11-20(18)23)21(24)14-16-8-7-9-17(22)13-16/h4-5,7-11,13,15H,2-3,6,12,14H2,1H3
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| InChIKey |
KURUPMPUIIQATM-UHFFFAOYSA-N
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| CAS Number |
CAS 864445-56-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4110-3. | |||
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