Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q6FF
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| Former ID |
DNC005302
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| Drug Name |
JWH-249
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| Synonyms |
JWH-249; 1-pentyl-3-(2-bromophenylacetyl)indole; 864445-60-3; UNII-H988KQV4U9; H988KQV4U9; CHEMBL363471; 2-(2-bromophenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone; DTXSID30658735; JWH 249; CGQRVOHECAULLB-UHFFFAOYSA-N; ZINC28461369; BDBM50170337; 2-(2-Bromo-phenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone; Ethanone, 2-(2-bromophenyl)-1-(1-pentyl-1H-indol-3-yl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H22BrNO
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| Canonical SMILES |
CCCCCN1C=C(C2=CC=CC=C21)C(=O)CC3=CC=CC=C3Br
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| InChI |
1S/C21H22BrNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3
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| InChIKey |
CGQRVOHECAULLB-UHFFFAOYSA-N
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| CAS Number |
CAS 864445-60-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4110-3. | |||
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