Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7MQ
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| Former ID |
DNC000468
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| Drug Name |
CP-100263
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| Synonyms |
3-Piperidinamine,N-[(2-methoxyphenyl)methyl]-2-phenyl-, (2S,3S)-; ACMC-1CCIL; SCHEMBL3951618; CTK4C0571; L007874
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| Drug Type |
Small molecular drug
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| Indication | Vomiting [ICD-11: MD90; ICD-10: R11; ICD-9: 787] | Investigative | [1] | |
| Company |
Pfizer
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H24N2O
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| Canonical SMILES |
COC1=CC=CC=C1CNC2CCCNC2C3=CC=CC=C3
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| InChI |
1S/C19H24N2O/c1-22-18-12-6-5-10-16(18)14-21-17-11-7-13-20-19(17)15-8-3-2-4-9-15/h2-6,8-10,12,17,19-21H,7,11,13-14H2,1H3/t17-,19-/m1/s1
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| InChIKey |
DTQNEFOKTXXQKV-IEBWSBKVSA-N
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| CAS Number |
CAS 872726-33-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Substance-P receptor (TACR1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51. | |||
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