Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q8LS
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| Former ID |
DNC009556
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| Drug Name |
2-[4-(2-Piperidin-1-ylethyl)phenoxy]benzothiazole
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| Synonyms |
Benzthiazole compound, 27b; SCHEMBL2168381; CHEMBL470753; BDBM24223
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H22N2OS
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| Canonical SMILES |
C1CCN(CC1)CCC2=CC=C(C=C2)OC3=NC4=CC=CC=C4S3
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| InChI |
1S/C20H22N2OS/c1-4-13-22(14-5-1)15-12-16-8-10-17(11-9-16)23-20-21-18-6-2-3-7-19(18)24-20/h2-3,6-11H,1,4-5,12-15H2
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| InChIKey |
DHHMVJVCMLXZBO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukotriene A-4 hydrolase (LTA4H) | Target Info | Inhibitor | [1] |
| Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Inhibitor | [1] | |
| BioCyc | Leukotriene biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Arachidonic Acid Metabolism | ||||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Potassium Channels | ||||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. J Med Chem. 2008 Jul 24;51(14):4150-69. | |||
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