Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QF6E
|
|||
| Former ID |
DIB008597
|
|||
| Drug Name |
Tridegin
|
|||
| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Terminated | [1] | |
| Company |
Biopharm
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Coagulation factor XIII (F13B) | Target Info | Modulator | [2], [3] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Pathwhiz Pathway | Coagulation | |||
| Reactome | Common Pathway of Fibrin Clot Formation | |||
| WikiPathways | Human Complement System | |||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008792) | |||
| REF 2 | Tridegin, a new peptidic inhibitor of factor XIIIa, from the blood-sucking leech Haementeria ghilianii. Biochem J. 1997 Jun 15;324 ( Pt 3):797-805. | |||
| REF 3 | Novel insights into structure and function of factor XIIIa-inhibitor tridegin.J Med Chem.2014 Dec 26;57(24):10355-65. | |||
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