Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QO6N
|
|||
| Drug Name |
MGD010
|
|||
| Indication | Autoimmune disease [ICD-11: 4A40-4A45; ICD-9: 279] | Phase 1 | [1] | |
| Company |
MacroGenicsRockville, MDTakeda Pharmaceuticals
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B-cell-specific glycoprotein B29 (CD79B) | Target Info | Modulator | [1] |
| Immunoglobulin gamma Fc receptor IIB (FCGR2B) | Target Info | Modulator | [1] | |
| KEGG Pathway | Phagosome | |||
| Osteoclast differentiation | ||||
| B cell receptor signaling pathway | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Staphylococcus aureus infection | ||||
| Tuberculosis | ||||
| Measles | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| IL4 Signaling Pathway | ||||
| Panther Pathway | B cell activation | |||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
| BCR signaling pathway | ||||
| Reactome | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | |||
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | ||||
| WikiPathways | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | |||
| Signaling by the B Cell Receptor (BCR) | ||||
| B Cell Receptor Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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