Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QT2F
|
|||
| Former ID |
DNC010221
|
|||
| Drug Name |
6-(4-methylpiperazin-1-yl)-9Hpurine
|
|||
| Synonyms |
6-(4-methylpiperazin-1-yl)-9H-purine; 6-(4-methylpiperazin-1-yl)-7H-purine; CHEMBL594152; 99172-01-7; SDCCGMLS-0065440.P001; 6-(4-methylpiperazin-1-yl)-9Hpurine; AC1LFNRL; Oprea1_666011; MLS000419169; 6-(4-methylpiperazinyl)purine; SCHEMBL13718480; MolPort-000-847-583; MolPort-000-384-358; HMS2684L19; ZINC213869; HMS1650E09; CCG-26902; BBL036787; STK630143; BDBM50304512; NSC510935; AKOS001427557; AKOS005562847; NSC-510935; MCULE-5386395090; SMR000319851; ST45178781; AB00588487-02; SR-01000104630; SR-01000104630-1; Z57745256
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H14N6
|
|||
| Canonical SMILES |
CN1CCN(CC1)C2=NC=NC3=C2NC=N3
|
|||
| InChI |
1S/C10H14N6/c1-15-2-4-16(5-3-15)10-8-9(12-6-11-8)13-7-14-10/h6-7H,2-5H2,1H3,(H,11,12,13,14)
|
|||
| InChIKey |
AXPCNBLIEMWMMG-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H4 receptor (H4R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization. Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.