Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QY3R
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| Former ID |
DNC006563
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| Drug Name |
Cbz-Ile-t-ButylhomoGlu-Ala-LeuVSMe
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| Synonyms |
CHEMBL207196; Cbz-Ile-t-ButylhomoGlu-Ala-LeuVSMe
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C35H56N4O9S
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| Canonical SMILES |
CCC(C)C(C(=O)NC(CCCC(=O)OC(C)(C)C)C(=O)NC(C)C(=O)NC(CC(C)C)C=CS(=O)(=O)C)NC(=O)OCC1=CC=CC=C1
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| InChI |
1S/C35H56N4O9S/c1-10-24(4)30(39-34(44)47-22-26-15-12-11-13-16-26)33(43)38-28(17-14-18-29(40)48-35(6,7)8)32(42)36-25(5)31(41)37-27(21-23(2)3)19-20-49(9,45)46/h11-13,15-16,19-20,23-25,27-28,30H,10,14,17-18,21-22H2,1-9H3,(H,36,42)(H,37,41)(H,38,43)(H,39,44)/b20-19+/t24-,25-,27+,28-,30-/m0/s1
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| InChIKey |
JWIOGOVPAFUFAB-OKNAZKIESA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
| Cathepsin S (CTSS) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Lysosome | |||
| Antigen processing and presentation | ||||
| Phagosome | ||||
| Tuberculosis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Reactome | Collagen degradation | |||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| Endosomal/Vacuolar pathway | ||||
| Degradation of the extracellular matrix | ||||
| WikiPathways | Class I MHC mediated antigen processing & presentation | |||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and c... J Med Chem. 2006 May 18;49(10):2953-68. | |||
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