Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R0EF
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| Former ID |
DIB003042
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| Drug Name |
AZD-7268
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| Synonyms |
Enkephalinergic receptor modulator (oral, depression, anxiety), AstraZeneca
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Phase 2 | [1], [2] | |
| Company |
AstraZeneca plc
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| Structure |
 |
Download2D MOL
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| Formula |
C29H30N4O2S
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| Canonical SMILES |
CN(CCO)C(=O)C1=CC=C(C=C1)C(=C2CCN(CC2)CC3=CSC=N3)C4=CC=CC5=C4N=CC=C5
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| InChI |
1S/C29H30N4O2S/c1-32(16-17-34)29(35)24-9-7-21(8-10-24)27(26-6-2-4-23-5-3-13-30-28(23)26)22-11-14-33(15-12-22)18-25-19-36-20-31-25/h2-10,13,19-20,34H,11-12,14-18H2,1H3
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| InChIKey |
ZJKUETLEJYCOBO-UHFFFAOYSA-N
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| CAS Number |
CAS 1018988-00-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor (OPR) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7824). | |||
| REF 2 | ClinicalTrials.gov (NCT01020799) AZD7268 Safety and Tolerability Study. U.S. National Institutes of Health. | |||
| REF 3 | EP patent application no. 2774991, Drug delivery system for use in the treatment or diagnosis of neurological disorders. | |||
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