Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R3HX
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| Former ID |
DIB011917
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| Drug Name |
RB-6145
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| Synonyms |
PD-144872
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Discontinued in Phase 1 | [1] | |
| Company |
BTG plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C8H14Br2N4O3
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| Canonical SMILES |
C1=CN(C(=N1)[N+](=O)[O-])CC(CNCCBr)O.Br
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| InChI |
1S/C8H13BrN4O3.BrH/c9-1-2-10-5-7(14)6-12-4-3-11-8(12)13(15)16;/h3-4,7,10,14H,1-2,5-6H2;1H
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| InChIKey |
XPBJPGMCFKYBBV-UHFFFAOYSA-N
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| CAS Number |
CAS 129448-97-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human Deoxyribonucleic acid (hDNA) | Target Info | Binder | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002473) | |||
| REF 2 | Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.. Br J Cancer. 1995 March; 71(3): 537-542. | |||
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