Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R8YJ
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| Former ID |
DNC006436
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| Drug Name |
N-ethyl-N-methyl-4-(pyridin-3-yl)but-3-yn-1-amine
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| Synonyms |
CHEMBL150948; N-ethyl-N-methyl-4-(pyridin-3-yl)but-3-yn-1-amine; BDBM50138487; 1-(3-Pyridinyl)-4-(methylethylamino)-1-butyne
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H16N2
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| Canonical SMILES |
CCN(C)CCC#CC1=CN=CC=C1
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| InChI |
1S/C12H16N2/c1-3-14(2)10-5-4-7-12-8-6-9-13-11-12/h6,8-9,11H,3,5,10H2,1-2H3
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| InChIKey |
DGPGTYZUJIIMAU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-4 (CHRNA4) | Target Info | Inhibitor | [1] |
| Neuronal acetylcholine receptor beta-2 (CHRNB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Cholinergic synapse | ||||
| Nicotine addiction | ||||
| Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
| Nicotine pharmacodynamics pathway | ||||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| Highly calcium permeable nicotinic acetylcholine receptors | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2013-6. | |||
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