Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RE4L
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| Former ID |
DIB009433
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| Drug Name |
KX2-361
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| Synonyms |
KX-02
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| Indication | Brain cancer [ICD-11: 2A00] | Phase 1 | [1] | |
| Glioblastoma multiforme [ICD-11: 2A00.0; ICD-9: 191] | Phase 1 | [2] | ||
| Company |
Kinex pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C24H24FN3O2
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| Canonical SMILES |
C1COCCN1C2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC(=CC=C4)F
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| InChI |
1S/C24H24FN3O2/c25-21-3-1-2-18(14-21)16-27-24(29)15-22-7-4-20(17-26-22)19-5-8-23(9-6-19)28-10-12-30-13-11-28/h1-9,14,17H,10-13,15-16H2,(H,27,29)
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| InChIKey |
CMKKPJNMYLOUCE-UHFFFAOYSA-N
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| CAS Number |
CAS 897016-26-1
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800041844) | |||
| REF 2 | ClinicalTrials.gov (NCT02326441) Safety, Tolerability & PK of KX2-361 in Subjects w Adv. Malignancies Refractory to Conventional Therapies. U.S. National Institutes of Health. | |||
| REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2206). | |||
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