Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RP8X
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| Former ID |
DNC002369
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| Drug Name |
UCL1972
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| Synonyms |
CHEMBL289855; UCL-1972; 1-[5-(4-nitrophenoxy)pentyl]pyrrolidine; 1-(5-(4-nitrophenoxy)pentyl)pyrrolidine; SCHEMBL490968; BDBM50089295; 1-[5-(4-Nitro-phenoxy)-pentyl]-pyrrolidine; L019446
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H22N2O3
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| Canonical SMILES |
C1CCN(C1)CCCCCOC2=CC=C(C=C2)[N+](=O)[O-]
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| InChI |
1S/C15H22N2O3/c18-17(19)14-6-8-15(9-7-14)20-13-5-1-2-10-16-11-3-4-12-16/h6-9H,1-5,10-13H2
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| InChIKey |
ITOJPDNONZGUKB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov. 2005 Feb;4(2):107-20. | |||
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