Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RX8U
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| Drug Name |
Indoline derivative 10
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| Synonyms |
PMID27646439-Compound-18
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| Drug Type |
Small molecular drug
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| Company |
JANSSEN PHARMACEUTICA NV
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H27N5O3
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| Canonical SMILES |
CC1=C(C2=CC=CC=C2N1)CC(=O)N3CCC4=C3C=CC(=C4)NC5=NC=NC6=CC(=C(C=C65)OC)OC
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| InChI |
1S/C29H27N5O3/c1-17-21(20-6-4-5-7-23(20)32-17)14-28(35)34-11-10-18-12-19(8-9-25(18)34)33-29-22-13-26(36-2)27(37-3)15-24(22)30-16-31-29/h4-9,12-13,15-16,32H,10-11,14H2,1-3H3,(H,30,31,33)
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| InChIKey |
XPDZQQQJQXPBBO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PRKR-like endoplasmic reticulum kinase (PERK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PRKR-like endoplasmic reticulum kinase (PERK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Jan;27(1):37-48. | |||
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