Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S0FZ
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| Former ID |
DCL000739
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| Drug Name |
Carisbamate
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| Synonyms |
Comfyde; JNJ 10234094; RWJ 333369; YKP 509; Carisbamate (USAN); JNJ-10234094; RWJ-333369; YKP-509; S-2-O-Carbamoyl-1-o-chlorophenyl-ethanol; [(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate
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| Drug Type |
Small molecular drug
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| Indication | Epilepsy [ICD-11: 8A60-8A68] | Phase 3 | [1] | |
| Focal dystonia [ICD-11: 8A02.1] | Phase 3 | [1] | ||
| Seizure disorder [ICD-11: 8A6Z] | Phase 3 | [1] | ||
| Company |
Johnson & Johnson
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| Structure |
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Download2D MOL |
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| Formula |
C9H10ClNO3
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| Canonical SMILES |
C1=CC=C(C(=C1)C(COC(=O)N)O)Cl
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| InChI |
1S/C9H10ClNO3/c10-7-4-2-1-3-6(7)8(12)5-14-9(11)13/h1-4,8,12H,5H2,(H2,11,13)/t8-/m1/s1
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| InChIKey |
OLBWFRRUHYQABZ-MRVPVSSYSA-N
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| CAS Number |
CAS 194085-75-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:135966
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| SuperDrug ATC ID |
N03AX19
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [1], [2], [3] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. | |||
| REF 2 | Pharmacological management of epilepsy: recent advances and future prospects. Drugs. 2008;68(14):1925-39. | |||
| REF 3 | Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22. | |||
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