Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S1AD
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| Former ID |
DIB005768
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| Drug Name |
Tridolgosir
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| Synonyms |
Swainsonine; Swainsonine hydrochloride; Tridolgosir hydrochloride; Carbohydrate processing inhibitors, GLYCODesign; GD-0039; Transforming growth factor beta inhibitors, GLYCODesign; GD-0039 analogs, GlycoDESIGN
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 2 | [1] | |
| Company |
GLYCODesign Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C8H15NO3
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| Canonical SMILES |
C1CC(C2C(C(CN2C1)O)O)O
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| InChI |
1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7-,8-/m1/s1
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| InChIKey |
FXUAIOOAOAVCGD-WCTZXXKLSA-N
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| CAS Number |
CAS 72741-87-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:9367
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Golgi alpha-mannosidase II (MAN2A1) | Target Info | Inhibitor | [2] |
| KEGG Pathway | N-Glycan biosynthesis | |||
| Metabolic pathways | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010383) | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010383) | |||
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