Drug Information
Drug General Information | Top | |||
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Drug ID |
D0S3EM
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Former ID |
DNCL003358
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Drug Name |
CAZ AVI
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Synonyms |
CAZ104
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Indication | Serious infection [ICD-11: 1H0Z; ICD-10: A00-B99; ICD-9: 001-139] | Phase 3 | [1] | |
Company |
AstraZeneca
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Target and Pathway | Top | |||
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Target(s) | Staphylococcus Beta-lactamase (Stap-coc blaZ) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01644643) Ceftazidime-Avibactam for the Treatment of Infections Due to Ceftazidime Resistant Pathogens. U.S. National Institutes of Health. | |||
REF 2 | NXL104 irreversibly inhibits the -lactamase from Mycobacterium tuberculosis. Biochemistry. 2012 Jun 5;51(22):4551-7. |
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