Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S4WQ
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| Former ID |
DNC010496
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| Drug Name |
1-(3-Chlorobenzyl)-1H-imidazole
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| Synonyms |
1-(3-Chlorobenzyl)-1H-imidazole; CHEMBL608437; 56643-68-6; 1-(3-Chlorobenzyl)imidazole; N-(3-chlorobenzyl)-imidazole; 1-(3-chlorobenzyl)-imidazole; SCHEMBL9661609; DARGVYVMURXBSO-UHFFFAOYSA-N; MolPort-008-647-602; BDBM50307215; ZINC35143438; AKOS003644458; MCULE-2532110476; 1-[(3-chlorophenyl)methyl]-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H9ClN2
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| Canonical SMILES |
C1=CC(=CC(=C1)Cl)CN2C=CN=C2
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| InChI |
1S/C10H9ClN2/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7H2
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| InChIKey |
DARGVYVMURXBSO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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