Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0S5ON
|
|||
Former ID |
DNC008259
|
|||
Drug Name |
1-(4-nitrophenethyl)pyrrolidine
|
|||
Synonyms |
1-(4-nitrophenethyl)pyrrolidine; CHEMBL273004; 168897-19-6; Pyrrolidine, 1-[2-(4-nitrophenyl)ethyl]-; SCHEMBL3156895; CTK0E5156; DTXSID90441428; YFOCDNYNVHXLJE-UHFFFAOYSA-N; BDBM50372307; ZINC29131362; 1-[2-(4-nitrophenyl)-ethyl]-pyrrolidine
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C12H16N2O2
|
|||
Canonical SMILES |
C1CCN(C1)CCC2=CC=C(C=C2)[N+](=O)[O-]
|
|||
InChI |
1S/C12H16N2O2/c15-14(16)12-5-3-11(4-6-12)7-10-13-8-1-2-9-13/h3-6H,1-2,7-10H2
|
|||
InChIKey |
YFOCDNYNVHXLJE-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 168897-19-6
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Histamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine Transport | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.