Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S5VI
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| Former ID |
DNC007002
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| Drug Name |
N-benzyl-4-cyclopentylpiperazine-1-carboxamide
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| Synonyms |
CHEMBL219757; N-benzyl-4-cyclopentylpiperazine-1-carboxamide; MolPort-009-268-235; ZINC32779618; BDBM50193214; AKOS027663191; MCULE-5408375837; Z332433676
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H25N3O
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| Canonical SMILES |
C1CCC(C1)N2CCN(CC2)C(=O)NCC3=CC=CC=C3
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| InChI |
1S/C17H25N3O/c21-17(18-14-15-6-2-1-3-7-15)20-12-10-19(11-13-20)16-8-4-5-9-16/h1-3,6-7,16H,4-5,8-14H2,(H,18,21)
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| InChIKey |
HVJJGTXESXSGPU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Ureas with histamine H3-antagonist receptor activity--a new scaffold discovered by lead-hopping from cinnamic acid amides. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5303-8. | |||
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