Drug Information
Drug General Information | Top | |||
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Drug ID |
D0S6QR
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Former ID |
DNC000330
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Drug Name |
BMS-204352
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Synonyms |
Flindokalner; MaxiPost; BMS-204352; 187523-35-9; Flindokalner [USAN:INN]; UNII-J57O328W4W; (3S)-3-(5-Chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1,3-dihydro-2H-indol-2-one; BMS 204352; J57O328W4W; 2H-Indol-2-one, 3-(5-chloro-2-methoxyphenyl)-3-fluoro-1,3-dihydro-6-(trifluoromethyl)-, (3S)-; Maxipost (TN); (s)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)indolin-2-one; (3S)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one; Bms204352; Flindokalner (USAN/INN); AC1Q4JQL; AC1L4WO7
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Drug Type |
Small molecular drug
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Indication | Nerve injury [ICD-11: ND56.4; ICD-10: T14.4] | Discontinued in Phase 3 | [1], [2] | |
Structure |
Download2D MOL |
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Formula |
C16H10ClF4NO2
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Canonical SMILES |
COC1=C(C=C(C=C1)Cl)C2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F
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InChI |
1S/C16H10ClF4NO2/c1-24-13-5-3-9(17)7-11(13)15(18)10-4-2-8(16(19,20)21)6-12(10)22-14(15)23/h2-7H,1H3,(H,22,23)/t15-/m0/s1
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InChIKey |
ULYONBAOIMCNEH-HNNXBMFYSA-N
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CAS Number |
CAS 187523-35-9
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PubChem Compound ID | ||||
PubChem Substance ID |
854075, 7979378, 9371783, 12015294, 14778990, 30418383, 47206138, 50069687, 57399695, 77679978, 103066770, 103081345, 103166547, 113456440, 117504687, 134223677, 134339779, 135129479, 135650001, 135697687, 142774089, 162807870, 164155442, 198964399, 223832302, 230762540, 241377263, 245560358, 249691349, 252158488, 252159870
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Target and Pathway | Top | |||
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Target(s) | Potassium channel unspecific (KC) | Target Info | Modulator | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2307). | |||
REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010536) | |||
REF 3 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. |
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