Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S7HC
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| Former ID |
DNC013821
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| Drug Name |
3-(4-Phenylpiperazin-1-carbonyl)coumarin
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| Synonyms |
CHEMBL486460; 3-(4-phenylpiperazine-1-carbonyl)-2H-chromen-2-one; 420099-59-8; 3-(4-Phenylpiperazin-1-carbonyl)coumarin; AC1LEC4F; CBMicro_029395; Oprea1_062891; ZINC99797; PEIQALYIIRRQAZ-UHFFFAOYSA-N; MolPort-000-467-605; STK414837; BDBM50244417; AKOS001407600; MCULE-7805538534; NCGC00306822-01; BIM-0029313.P001; ST4080681; AB00094693-01; 3-[(4-phenylpiperazinyl)carbonyl]chromen-2-one; AB00094693-02; 3-(4-phenylpiperazine-1-carbonyl)chromen-2-one; SR-01000218055; Chromen-2-one, 3-(4-phenylpiperazine-1-carbonyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H18N2O3
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| Canonical SMILES |
C1CN(CCN1C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4OC3=O
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| InChI |
1S/C20H18N2O3/c23-19(17-14-15-6-4-5-9-18(15)25-20(17)24)22-12-10-21(11-13-22)16-7-2-1-3-8-16/h1-9,14H,10-13H2
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| InChIKey |
PEIQALYIIRRQAZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues. Bioorg Med Chem. 2008 Sep 1;16(17):8011-21. | |||
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