Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S7VZ
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| Former ID |
DIB013782
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| Drug Name |
WAY-100289
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| Synonyms |
Endo-2-(Cyclopropylmethoxy)-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-ylcarbamoyl)benzamide maleate; Endo-1-[2-(Cyclopropylmethoxy)benzoyl]-3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)urea maleate
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Discontinued in Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H27N3O3
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| Canonical SMILES |
CN1C2CCC1CC(C2)NC(=O)NC(=O)C3=CC=CC=C3OCC4CC4
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| InChI |
1S/C20H27N3O3/c1-23-15-8-9-16(23)11-14(10-15)21-20(25)22-19(24)17-4-2-3-5-18(17)26-12-13-6-7-13/h2-5,13-16H,6-12H2,1H3,(H2,21,22,24,25)/t14?,15-,16+
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| InChIKey |
VFRIHPWRNNTKEX-MQVJKMGUSA-N
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| CAS Number |
CAS 136013-69-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3 receptor (5HT3R) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001552) | |||
| REF 2 | The selective 5-HT3 receptor antagonist, WAY100289, enhances spatial memory in rats with ibotenate lesions of the forebrain cholinergic projection system. Psychopharmacology (Berl). 1995 Feb;117(3):318-32. | |||
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