Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SQ0T
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| Former ID |
DNC011538
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| Drug Name |
C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine
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| Synonyms |
CHEMBL292558; C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine; BDBM50127603
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H11N3
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| Canonical SMILES |
C1C(C1C2=CN=CN2)CN
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| InChI |
1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6+/m1/s1
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| InChIKey |
LMFNLINKCDGRTE-RITPCOANSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist f... J Med Chem. 2003 May 8;46(10):1980-8. | |||
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