Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T4ZI
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| Former ID |
DNC011758
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| Drug Name |
6-Chloro-2-(3-nitro-phenyl)-chromen-4-one
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| Synonyms |
CHEMBL59263; 127767-40-2; 4H-1-Benzopyran-4-one, 6-chloro-2-(3-nitrophenyl)-; 6-chloro-2-(3-nitrophenyl)chromen-4-one; ACMC-20mskm; 3'-Nitro-6-chloroflavone; AC1NMK14; 6-chloro-3' -nitroflavone; CTK0C1861; DTXSID20407496; AKOS001600357; EU-0068162; SR-01000400460
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H8ClNO4
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| Canonical SMILES |
C1=CC(=CC(=C1)[N+](=O)[O-])C2=CC(=O)C3=C(O2)C=CC(=C3)Cl
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| InChI |
1S/C15H8ClNO4/c16-10-4-5-14-12(7-10)13(18)8-15(21-14)9-2-1-3-11(6-9)17(19)20/h1-8H
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| InChIKey |
DKCAUMRZSZVJCP-UHFFFAOYSA-N
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| CAS Number |
CAS 127767-40-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor, Bioorg. Med. Chem. Lett. 7(15):2003-2008 (1997). | |||
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