Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T7WL
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| Former ID |
DIB012775
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| Drug Name |
Pirmenol
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| Synonyms |
Pimenol; Pirmavar; Pirmenol hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Approved | [1] | |
| Company |
Pfizer Inc
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| Structure |
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Download2D MOL |
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| Formula |
C22H30N2O
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| Canonical SMILES |
CC1CCCC(N1CCCC(C2=CC=CC=C2)(C3=CC=CC=N3)O)C
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| InChI |
1S/C22H30N2O/c1-18-10-8-11-19(2)24(18)17-9-15-22(25,20-12-4-3-5-13-20)21-14-6-7-16-23-21/h3-7,12-14,16,18-19,25H,8-11,15,17H2,1-2H3/t18-,19+,22?
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| InChIKey |
APUDBKTWDCXQJA-QIDMFYOTSA-N
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| CAS Number |
CAS 68252-19-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:135436
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [1], [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Pirmenol, a new antiarrhythmic drug with potassium- and sodium-channel blocking activity; a voltage-clamp study in rabbit Purkinje fibres. Naunyn Schmiedebergs Arch Pharmacol. 1990 May;341(5):462-71. | |||
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