Drug Information
Drug General Information | Top | |||
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Drug ID |
D0T7WW
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Drug Name |
4-(2-cyclohexylethoxy) aniline derivative 4
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Synonyms |
PMID28454500-Compound-90
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Drug Type |
Small molecular drug
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Company |
Korea institute of radiological & medical sciences, S
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Structure |
Download2D MOL |
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Formula |
C24H29BrN2O4
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Canonical SMILES |
C1CCC(CC1)CCOC2=CC=C(C=C2)NC(=O)COCC(=O)NC3=CC(=CC=C3)Br
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InChI |
1S/C24H29BrN2O4/c25-19-7-4-8-21(15-19)27-24(29)17-30-16-23(28)26-20-9-11-22(12-10-20)31-14-13-18-5-2-1-3-6-18/h4,7-12,15,18H,1-3,5-6,13-14,16-17H2,(H,26,28)(H,27,29)
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InChIKey |
SUIJKJPCTOXCER-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target Info | Inhibitor | [1] |
Target's Patent Info | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target's Patent Info | [1] | |
KEGG Pathway | Protein processing in endoplasmic reticulum | |||
NetPath Pathway | IL5 Signaling Pathway | |||
WikiPathways | Oxidative Stress | |||
Transcriptional activation by NRF2 | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Aryl Hydrocarbon Receptor Pathway | ||||
Mesodermal Commitment Pathway | ||||
Aryl Hydrocarbon Receptor | ||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
Arylhydrocarbon receptor (AhR) signaling pathway |
References | Top | |||
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REF 1 | Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):763-785. |
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