Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T8JU
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| Former ID |
DNC010509
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| Drug Name |
1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole
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| Synonyms |
1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole; 1192811-38-3; CHEMBL591697; SCHEMBL1950743; DTXSID90668214; ZINC45338026; BDBM50307235; AKOS016012754; KB-214961; AJ-110482; AX8249207
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H16N2O
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| Canonical SMILES |
COC1=CC=C(C=C1)CN2C=NC=C2C3=CC=CC=C3
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| InChI |
1S/C17H16N2O/c1-20-16-9-7-14(8-10-16)12-19-13-18-11-17(19)15-5-3-2-4-6-15/h2-11,13H,12H2,1H3
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| InChIKey |
AZQFSYIIRUWICT-UHFFFAOYSA-N
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| CAS Number |
CAS 1192811-38-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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