Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T9LR
|
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| Former ID |
DNCL003801
|
|||
| Drug Name |
Liprotamase
|
|||
| Synonyms |
LY3031642
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|
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| Indication | Cystic fibrosis [ICD-11: CA25; ICD-10: E84, E84.9; ICD-9: 277] | Phase 3 | [1] | |
| Company |
Lilly
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Chymotrypsin (CTR) | Target Info | Modulator | [2] |
| Pancreatic alpha-amylase (AMY2A) | Target Info | Modulator | [2] | |
| Pancreatic triacylglycerol lipase (PNLIP) | Target Info | Modulator | [2] | |
| BioCyc | Triacylglycerol degradation | |||
| Retinol biosynthesis | ||||
| KEGG Pathway | Glycerolipid metabolism | |||
| Metabolic pathways | ||||
| Pancreatic secretion | ||||
| Fat digestion and absorption | ||||
| Vitamin digestion and absorption | ||||
| Reactome | Retinoid metabolism and transport | |||
| WikiPathways | Visual phototransduction | |||
| Lipid digestion, mobilization, and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00500084) Phase III ALTU-135 CP Safety Trial. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of Anthera Pharmaceuticals. | |||
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