Drug Information
Drug General Information | Top | |||
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Drug ID |
D0TM4R
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Drug Name |
Piperazine carbamate/urea derivative 6
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Synonyms |
PMID29334795-Compound-44
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Drug Type |
Small molecular drug
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Company |
Novartis AG
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Structure |
Download2D MOL |
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Formula |
C18H28N4O3
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Canonical SMILES |
CC(C)N1CCN(CC1)C(=O)OC2CCN(CC2)C3=CNC(=O)C=C3
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InChI |
1S/C18H28N4O3/c1-14(2)20-9-11-22(12-10-20)18(24)25-16-5-7-21(8-6-16)15-3-4-17(23)19-13-15/h3-4,13-14,16H,5-12H2,1-2H3,(H,19,23)
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InChIKey |
ONRCNWHOGZJSOB-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Histamine H3 receptor (H3R) | Target Info | Ligand | [1] |
Target's Patent Info | Histamine H3 receptor (H3R) | Target's Patent Info | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Histamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine Transport | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Progress in the development of histamine H3 receptor antagonists/inverse agonists: a patent review (2013-2017).Expert Opin Ther Pat. 2018 Mar;28(3):175-196. |
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